Starting an antidepressant often comes with two competing emotions: relief that you’re finally getting help, and frustration that you don’t see improvement immediately. Many adults begin treatment hoping they’ll feel noticeably better within days. If your current medication provides only partial relief or has plateaued, explore our clinical insights on when an antidepressant is not working. When that doesn’t happen, it’s easy to assume the medication is failing, or worse, tha